Which Phrase Does NOT Describe an Aspect of the Nucleotide

Which phrase does NOT describe an aspect of the nucleotide addition reaction catalyzed by E. coli DNA Pol III?

A) activation of the 3' OH of the newly synthesized strand by a metal ion
B) a properly positioned phosphate
C) specific protein/base-pair interactions in the major groove
D) charge stabilization of all three phosphates on the substrate
E) All of these are important aspects of the addition reaction.