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The Linking Number (Lk) of a Closed-Circular, Double-Stranded DNA Molecule

Question 7

Multiple Choice

The linking number (Lk) of a closed-circular, double-stranded DNA molecule is changed by:


A) breaking a strand, then rejoining it.
B) breaking a strand, unwinding or rewinding the DNA, then rejoining it.
C) breaking all hydrogen bonds in the DNA.
D) supercoiling without the breaking of any phosphodiester bonds.
E) underwinding without the breaking of any phosphodiester bonds.

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