Which statement does NOT contradict the one gene-one enzyme hypothesis?

Question

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All of the statements listed are consistent with the one gene-one enzyme hypothesis, which states that each gene codes for a single enzyme. Statement A acknowledges that some proteins are composed of multiple subunits, each with their own gene encoding them. Statements B and C mention the existence of RNA molecules that are not enzymes, but these do not contradict the one gene-one enzyme hypothesis. Finally, statement D simply notes that regulatory sequences outside of coding regions can influence gene expression, which is also compatible with the one gene-one enzyme hypothesis. Therefore, the only logical conclusion is that none of these statements contradicts the one gene-one enzyme hypothesis.

Which Statement Does NOT Contradict the One Gene-One Enzyme Hypothesis