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The Overall Compaction of a Eukaryotic Chromosome Is Greater Than

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The overall compaction of a eukaryotic chromosome is greater than ____-fold. The first level is nucleosome formation, which compacts about ____-fold. Next is the 30 nm fiber, which compacts about ____-fold overall. Higher order folding involves association of the DNA with a nuclear _____, which contains large amounts of ____ and ____.

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