Which statement about energy conservation in the mitochondrion is FALSE?
A) Drugs that inhibits the ATP synthase will also inhibit the flow of electrons down the chain of carriers.
B) For oxidative phosphorylation to occur, it is essential to have a closed membranous structure with an inside and an outside.
C) The yield of ATP per mole of oxidizable substrate depends on the substrate.
D) Uncouplers (such as dinitrophenol) have exactly the same effect on electron transfer as inhibitors such as cyanide; both block further electron transfer to oxygen.
E) Uncouplers "short circuit" the proton gradient, thereby dissipating the proton motive force as heat.

Question

Quizplus · Accepted Answer

Uncouplers such as dinitrophenol have a different effect on electron transfer compared to inhibitors such as cyanide. Uncouplers allow the electrons to continue flowing down the electron transport chain but they "short circuit" the proton gradient, dissipating the proton motive force as heat. Inhibitors, on the other hand, block further electron transfer to oxygen, thus preventing the generation of ATP.

Which Statement About Energy Conservation in the Mitochondrion Is FALSE