Mammals produce heat by using which endogenous uncoupling agent? A) the small molecule 2-4-dinitrophenol synthesized by the cell B) the protein thermogenin C) the protein thioredoxin D) the protein cytochrome c E) a modified form of the F_oF₁ ATPase

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Quizplus · Accepted Answer

Mammals produce heat by using the protein thermogenin, also known as uncoupling protein 1 (UCP1), which is an endogenous uncoupling agent located on the inner mitochondrial membrane of brown adipose tissue. It allows protons to leak across the membrane, which dissipates the proton gradient and reduces the efficiency of ATP production, thereby generating heat instead. The other options listed do not serve as endogenous uncoupling agents in mammals.

Mammals Produce Heat by Using Which Endogenous Uncoupling Agent