Which pathway is likely to be affected by a deficiency in carnitine?

Question

Quizplus · Accepted Answer

Carnitine is important for the transport of long-chain fatty acids into the mitochondria for β-oxidation. Deficiency in carnitine would result in impaired β-oxidation of long-chain fatty acids, which is the pathway of choice for energy production in muscles, heart, and liver. The pathway for β-oxidation of short-chain fatty acids (option A) does not rely on carnitine for transport into the mitochondria. Option C is incorrect because uptake of fatty acids from the bloodstream occurs via fatty acid transport proteins (FATPs), which are independent of carnitine. Therefore, option D (all of the answers are correct) and option E (none of the answers are correct) are incorrect.

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