Which statement is NOT associated with controlling the rate of glycogen synthesis in hepatocytes? A) Insulin stimulates the translocation of GLUT 2 transporters to the plasma membrane. B) Insulin induces the synthesis of hexokinase IV. C) Glucagon inhibits the activity of glycogen synthase via covalent modification. D) Insulin activates phosphorylase a phosphatase. E) Epinephrine and insulin both result in the phosphorylation of the glycogen targeting protein G_M.

Question

Quizplus · Accepted Answer

Insulin does stimulate the translocation of GLUT 4 (not GLUT 2) transporters to the plasma membrane in muscle and fat cells, not hepatocytes, and this process is primarily associated with increasing glucose uptake rather than directly controlling the rate of glycogen synthesis. In hepatocytes, glucose uptake is not dependent on insulin-mediated GLUT transporter translocation.

Which Statement Is NOT Associated with Controlling the Rate of Glycogen