Given that the $\Delta$ G'0^o values for the hydrolysis of glucose 1-phosphate and glucose 6-phosphate are approximately -21 kJ/mol and -14 kJ/mol, respectively, which statement is TRUE regarding the following isomerizations? glucose 1-phosphate $\leftrightarrow$ glucose 6-phosphate A) Under cellular conditions the direction of the reaction depends on the concentrations of glucose 1-phosphate and glucose 6-phosphate. B) The overall rate of this reaction is relatively slow. C) An increase in entrophy "drives" this reaction. D) The value of $\Delta$ G'^ofor this isomerization reaction is small and positive. E) All the statements are true for the isomerization reaction shown above.

Question

Quizplus · Accepted Answer

The given free energy values indicate that the isomerization reaction from glucose 1-phosphate to glucose 6-phosphate is spontaneous and exergonic. However, the direction of the reaction will depend on the concentrations of the two molecules present in the cell. If the concentration of glucose 6-phosphate is high, then the equilibrium will shift towards glucose 1-phosphate, and vice versa. The given information does not provide any indication about the overall rate of the reaction, the role of entropy, or the value of the free energy change for this reaction. Therefore, options B, C, and D are incorrect.

Given That The Δ\DeltaΔ G'0o Values for the Hydrolysis of Glucose 1-Phosphate and Glucose

Given That The $\Delta$ G'0^o Values for the Hydrolysis of Glucose 1-Phosphate and Glucose