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Lactate Dehydrogenase Catalyzes the Reversible Reaction:
Pyruvate + NADH \rightarrow Lactate + NAD+
Given the Following Facts (A) Tell in H+

Question 104

Short Answer

Lactate dehydrogenase catalyzes the reversible reaction:
pyruvate + NADH + H+ \rightarrow lactate + NAD+
Given the following facts (a) tell in which direction the reaction will tend to go if NAD+, NADH, pyruvate, and lactate were mixed, all at 1 M concentrations, in the presence of lactate dehydrogenase at pH 7; (b) calculate Δ\Delta G'° for this reaction. Show your work.
NAD+ + H+ + 2e- \rightarrow NADH
E'° = -0.32 V
pyruvate + 2H+ + 2e- \rightarrow lactate
E'° = -0.19 V
The Faraday constant,  Lactate dehydrogenase catalyzes the reversible reaction: pyruvate + NADH + H<sup>+</sup> \rightarrow  lactate + NAD<sup>+</sup> Given the following facts (a) tell in which direction the reaction will tend to go if NAD<sup>+</sup>, NADH, pyruvate, and lactate were mixed, all at 1 M concentrations, in the presence of lactate dehydrogenase at pH 7; (b) calculate  \Delta G'° for this reaction. Show your work. NAD<sup>+ </sup>+ H<sup>+</sup> + 2e<sup>-</sup>  \rightarrow   NADH E'° = -0.32 V pyruvate + 2H<sup>+</sup> + 2e<sup>-</sup>  \rightarrow   lactate E'° = -0.19 V The Faraday constant,  , is 96.48 kJ/V · mol. , is 96.48 kJ/V · mol.

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