Which protein is phosphorylated in response to an insulin/insulin receptor interaction?

Question

Quizplus · Accepted Answer

IRS-1 and phosphatidyl inositol-4,5-bisphosphate are both phosphorylated in response to insulin/insulin receptor interactions. IRS-1 is directly phosphorylated by the insulin receptor, leading to downstream signaling. Phosphatidyl inositol-4,5-bisphosphate is phosphorylated to produce phosphatidylinositol (3,4,5)-trisphosphate (PIP3), a critical step in the insulin signaling pathway.

Which Protein Is Phosphorylated in Response to an Insulin/insulin Receptor