Malignant proliferation of plasma cells with osteolytic bone lesions and the presence of monoclonal immunoglobulin in the serum describe:

Question

Quizplus · Accepted Answer

The description is classically seen in multiple myeloma, which is a type of plasma cell myeloma. The malignant plasma cells release monoclonal immunoglobulin which can cause osteolytic bone lesions. Waldenström macroglobulinemia is also associated with monoclonal immunoglobulin but does not typically have osteolytic bone lesions. Marginal zone B-cell lymphoma and follicle center lymphoma do not have the same characteristics as multiple myeloma.

Malignant Proliferation of Plasma Cells with Osteolytic Bone Lesions and the Presence