A patient with a previously compensated hereditary spherocytosis has a severe drop in hemoglobin after a parvovirus infection. This represents what type of crisis?

Question

Quizplus · Accepted Answer

Parvovirus infection can lead to aplastic crisis in patients with hereditary spherocytosis. This is because parvovirus B19 specifically targets and destroys erythroid progenitor cells in the bone marrow, leading to a sudden halt in red blood cell production.

A Patient with a Previously Compensated Hereditary Spherocytosis Has a Severe