What characteristic red cell shape is associated with extravascular hemolysis?

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Quizplus · Accepted Answer

Spherocytes are associated with extravascular hemolysis because their shape makes them more prone to removal by macrophages in the spleen and liver. Spherocytes are small, round, and lack central pallor. Schistocytes, or fragmented cells, are associated with intravascular hemolysis due to mechanical shear forces in small blood vessels. Target cells and burr cells can be seen in various conditions, but are not specifically associated with extravascular hemolysis.

What Characteristic Red Cell Shape Is Associated with Extravascular Hemolysis