How Can Cytokines,which Help Fight Infection,contribute to Heart Disease,stroke,and Other

How can cytokines,which help fight infection,contribute to heart disease,stroke,and other illness?

A) High stress causes the lymphocytes to bind to cytokine receptors, which in turn weaken the body's defences against bacteria and viruses.
B) High stress causes the adrenal glands to release cortisol, which in turn inhibits the cytokines.
C) High stress leads to high cytokine levels, which in turn leads to chronic inflammation.
D) High stress leads to low cytokine levels, which in turn excite norepinephrine receptors.