Which level of protein structure is not affected by denaturation?

Question

Quizplus · Accepted Answer

Denaturation refers to the alteration of a protein's shape, causing it to lose its function. This is due to the disruption of its non-covalent bonds such as hydrogen bonds, ionic bonds, and hydrophobic interactions which keep the protein folded in its native state. Denaturation affects the secondary, tertiary, and quaternary levels of protein structure, but it does not affect the primary structure. The primary structure is determined by the sequence of amino acids in the polypeptide chain, which is held together by covalent peptide bonds, and denaturation does not break these bonds.

Which Level of Protein Structure Is Not Affected by Denaturation