Which statement describes the missing piece of evidence that would confirm that folic acid reduces the risk of cardiovascular disease?

Question

Quizplus · Accepted Answer

The missing piece of evidence to confirm that folic acid reduces the risk of cardiovascular disease is intervention trials that show that folic acid supplementation reduces the risk of cardiovascular disease. While observational studies can suggest a relationship, only intervention trials can prove a cause-and-effect relationship between folic acid supplementation and reduced risk of cardiovascular disease. Additionally, studies that show a direct relationship between homocysteine levels and cardiovascular disease risk or an inverse relationship between folic acid and cardiovascular disease risk can suggest potential mechanisms for the protective effect of folic acid, but they do not provide direct evidence for the effect of folic acid supplementation on cardiovascular disease risk.

Which Statement Describes the Missing Piece of Evidence That Would