You create a cell that has a mutation in a receptor protein that binds a signaling molecule, which is also produced by the same cell. When you overexpress the signaling molecule produced by this cell, nothing happens. What is defective in this cell?
A)endocrine signaling
B)contact-dependent signaling
C)paracrine signaling
D)autocrine signaling

Question

Quizplus · Accepted Answer

The mutation in the receptor protein suggests that the signaling molecule produced by the cell is an autocrine signal that binds to receptors on the same cell. Overexpressing this signal should have an effect on the cell's behavior, unless the receptor is no longer functioning properly due to the mutation. This indicates a defect in autocrine signaling.

You Create a Cell That Has a Mutation in a Receptor