Why don't steroid hormones bind to transmembrane cell-surface receptors?
A)Steroid hormones don't require receptors because they bind directly to DNA.
B)Steroid hormones are not signaling molecules.
C)Steroid hormones are nonpolar and, therefore, cannot bind to receptors.
D)Steroid hormones are nonpolar and, therefore, are able to cross the cell's plasma membrane, thus binding to receptors inside the cell.

Question

Quizplus · Accepted Answer

Steroid hormones are nonpolar and can easily cross the cell's plasma membrane. Therefore, they can bind to receptors inside the cell, such as nuclear receptors, without requiring transmembrane cell-surface receptors.

Why Don't Steroid Hormones Bind to Transmembrane Cell-Surface Receptors