What causes the inactivation of a G protein?
A)The alpha subunit catalyzes the hydrolysis of GTP to GDP and inorganic phosphate.
B)The beta and gamma subunits trigger the hydrolysis of GTP to GDP.
C)A phosphatase removes the inorganic phosphate group from GTP.
D)The inactive receptor catalyzes the replacement of GTP by GDP.

Question

Quizplus · Accepted Answer

The inactivation of a G protein is caused by the alpha subunit catalyzing the hydrolysis of GTP to GDP and inorganic phosphate. This results in a conformational change that leads to the dissociation of the alpha subunit from the beta-gamma subunits and the receptor, returning the system to its inactive state.

What Causes the Inactivation of a G Protein