The figure below shows a three-dimensional model of the enzyme lysozyme (A) and a map of the location of the important binding and catalytic amino acids that participate at the active site (
B). Why are the amino acids of an enzyme that participate in substrate binding and in catalytic activity widely separated on the polypeptide chain, rather than being close together in the primary sequence?

Question

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The Answer of The figure below shows a three-dimensional model of the enzyme lysozyme (A) and a map of the location of the important binding and catalytic amino acids that participate at the active site (
B). Why are the amino acids of an enzyme that participate in substrate binding and in catalytic activity widely separated on the polypeptide chain, rather than being close together in the primary sequence?

The Figure Below Shows a Three-Dimensional Model of the Enzyme