Which of the Statements Below About Hormone Effects on Behavior

Which of the statements below about hormone effects on behavior is NOT true?

A) Most hormones are secreted into the circulation and thus have wide-ranging targets.
B) Hormones can affect multiple cells in the target simultaneously.
C) Compared to hormone action, neurons are much less specific in their actions.
D) Target tissues must have receptors for a particular hormone in order for a response to be elicited.
E) Hormone-mediated responses may be different between the sexes.