How would a rapid evolutionary change in cell-surface proteins in bacteria affect the innate immune system?

Question

Quizplus · Accepted Answer

The innate immune system relies on the recognition of pathogens through receptors, such as Toll-like receptors (TLRs) on phagocytes, which recognize specific patterns on the surface of bacteria. If there is a rapid evolutionary change in cell-surface proteins in bacteria, the TLRs may not be able to recognize the new proteins, which would weaken the ability of the innate immune system to respond to the pathogen.

How Would a Rapid Evolutionary Change in Cell-Surface Proteins in Bacteria