A Woman Goes to the Doctor and Is Diagnosed with Rheumatoid

A woman goes to the doctor and is diagnosed with rheumatoid arthritis. What factors led to her developing this disease?

A) Some of her T cells were not positively selected.
B) Some of her T cells were not negatively selected.
C) Some of her T cells are recognizing and responding to her self antigens.
D) Some of her T cells are not recognizing and associating with her MHC proteins.