How do immune cells with sensitivity to self-antigens become eliminated?

Question

Quizplus · Accepted Answer

Immune cells with sensitivity to self-antigens can lead to autoimmune diseases if they are not eliminated. To ensure self-tolerance, immune cells undergo negative selection in the thymus and bone marrow. During negative selection, cells that recognize self-antigens are eliminated by inducing cell death (apoptosis). This process helps to prevent autoimmune diseases by removing self-reactive immune cells from the body. Therefore, choice C is the best answer as it directly states that self-reactive cells undergo cell death.

How Do Immune Cells with Sensitivity to Self-Antigens Become Eliminated