Why Did England Consider Spain Its Enemy by the Late

Why did England consider Spain its enemy by the late 1500s?

A) Because of religious differences: England had officially broken with the Roman Catholic Church,while Spain was devoutly Catholic.
B) Because of the Spanish Armada's successful invasion of Great Britain in 1588.
C) Because Spain had allied with France to invade English colonies in the New World.
D) Because one of Henry VIII's beheaded wives was a Spanish princess,and the Spanish government announced it would be at war with England until Henry apologized.
E) Because both the English and Spanish royal families laid claim to the Irish throne.