What is the significance of the fact that the loop of Henle extends into the medulla of the kidney with sections that run antiparallel to one another?

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Quizplus · Accepted Answer

The loop of Henle generates the concentration gradient in the kidney by actively transporting ions such as sodium, chloride, and potassium out of the ascending limb and into the interstitial fluid. The antiparallel arrangement of the descending and ascending limbs allows for countercurrent exchange, which helps to maintain the concentration gradient.

What Is the Significance of the Fact That the Loop