The interior of a neuron is more negative than the outside due to the presence of:

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Quizplus · Accepted Answer

The interior of a neuron is more negative than the outside due to the contribution of both proteins and chloride ions. Proteins are negatively charged and cannot pass through the cell membrane, which contributes to the negative charge inside the neuron. Chloride ions (Cl-) are also negatively charged and are more concentrated inside the neuron than outside, contributing to the negative charge inside the neuron. Hydroxyl groups (OH^-) are not involved in the maintenance of the negative charge of the neuron interior.

The Interior of a Neuron Is More Negative Than the Outside