If the first nucleotide after the promoter on the top DNA strand is changed from G to T, what would the resulting nucleotide be on the mRNA?
A)A
B)C
C)T
D)G

Question

Quizplus · Accepted Answer

During transcription, RNA polymerase synthesizes mRNA in a 5' to 3' direction, using the DNA template strand. The mRNA is complementary to the DNA template strand. If the DNA sequence changes from G to T on the coding strand (which corresponds to the top strand mentioned), the base on the mRNA that pairs with this changed nucleotide would be A, because RNA uses uracil (U) instead of thymine (T), but since the option for U is not given and the question likely refers to the base that pairs with T during transcription, A (adenine) is the correct answer.

If the First Nucleotide After the Promoter on the Top