Arrange the steps in RNA splicing in order from earliest to latest. 1 - exon ends are covalently joined together
2 - components of the spliceosome bind conserved regions in the intron and bring them together in close proximity
3 - acceptor splice site is cut.
4 - donor splice site is cut and the end of the intron is joined covalently to the branch site
A)3, 4, 1, 2
B)2, 4, 3, 1
C)2, 3, 1, 4
D)3, 2, 4, 1
E)3, 1, 2, 4

Question

Quizplus · Accepted Answer

The first step in RNA splicing is the binding of components of the spliceosome to conserved regions in the intron (Step 2). Then the donor splice site is cut and the end of the intron is joined covalently to the branch site (Step 4). Next, the acceptor splice site is cut (Step 3) and finally the exon ends are covalently joined together (Step 1). The correct order is therefore 2, 4, 3, 1 or choice B.

Arrange the Steps in RNA Splicing in Order from Earliest