In domestic cats, the coat-color pattern known as calico is an example of:

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Calico coat color in cats is an example of all the listed mechanisms: it involves gene regulation at the chromosome level, dosage compensation, epigenetic regulation, and X-inactivation. This is because the genes for coat color are located on the X chromosome, and in females (who have two X chromosomes), one of the X chromosomes is inactivated in each cell in a process known as X-inactivation or Lyonization. This leads to patches of cells expressing one allele and other patches expressing the alternate allele, resulting in the distinctive calico pattern. This process is a form of dosage compensation, is regulated at the chromosome level, and involves epigenetic changes to the inactivated X chromosome.

In Domestic Cats, the Coat-Color Pattern Known as Calico Is