In a study of concordance, a sample of identical twins was evaluated for adult-onset diabetes. The data below were collected for this trait:
1. In 36 identical twin pairs, both showed adult-onset diabetes.
2. In 40 identical twin pairs, only one s3. In 336 identical twin pairs, neither showed adult-onset diabetes.
Item 3 shows that a majority of identical twins do not have the disease, and gives us the most information with regard to concordance of the trait.howed adult-onset diabetes.

Question

Quizplus · Accepted Answer

The statement about item 3 providing the most information regarding concordance is incorrect. Concordance in identical twins is more informatively assessed by comparing the number of twin pairs where both have the disease to the number where only one does. The data showing both twins with the disease (36 pairs) versus only one twin with the disease (40 pairs) directly addresses concordance, not the number of pairs where neither has the disease (336 pairs).

In a Study of Concordance, a Sample of Identical Twins