Sometimes certain diseases affect all sons of an affected father, even when the mother is unaffected. What is the BEST explanation of this?

Question

Quizplus · Accepted Answer

If the disease-related gene is located on the Y chromosome, all sons of an affected father will inherit the gene and be affected, regardless of whether the mother is affected or not. This is because the Y chromosome is passed from father to son and does not recombine with the mother's X chromosome during sexual reproduction.

Sometimes Certain Diseases Affect All Sons of an Affected Father