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Your Grandmother Has a Rare Disease for Which a New

Question 188

Multiple Choice

Your grandmother has a rare disease for which a new genetic test has just been developed. If you are interested in a genetic test to determine whether you are affected, which of the following would you need to know to BEST interpret your test?


A) if you have one or two copies of a dominant allele
B) your father's genotype
C) the penetrance of disease in people of your genotype
D) the degree of variable expressivity if you lack a copy of the affected allele

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