A patient is about to receive chemotherapy and the doctor is concerned with dispensing the correct dosage. Certain people cannot metabolize this type of chemical because they have a mutation that changes a codon for valine into one for asparagine. How would such a mutation be classified?

Question

Quizplus · Accepted Answer

The mutation described here affects a single nucleotide, which is a hallmark of a single nucleotide polymorphism (SNP). RFLP (restriction fragment length polymorphism) and CNV (copy number variation) refer to different types of genetic variation that do not involve a single nucleotide change. PCR (polymerase chain reaction) is a laboratory technique used to amplify DNA and is not related to classifying mutations.

A Patient Is About to Receive Chemotherapy and the Doctor