Chromosome Painting (See Figure 13

Chromosome painting (see Figure 13.14) is achieved by labeling various DNA fragments with different fluorescent molecules and hybridizing those to human chromosomes spread on a microscope slide. The result, if done properly, is that each chromosome can be visualized as having a different color.

Photo credit: NHGRI, www.genome.gov. Given the ability to paint each chromosome differently, what else must be TRUE?

A) No similar gene sequences are found on more than one chromosome.
B) Each chromosome must have at least some sequences not found on other chromosomes.
C) Transposable element sequences must cluster together on single chromosomes.
D) Each chromosome condenses around histones in its own way.
E) None of the other answer choices is correct.