According to the Baltimore system, the major groups of viruses are classified according to their:

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The Baltimore system classifies viruses based on the type of genome they have, such as double-stranded DNA, single-stranded RNA, or double-stranded RNA. This classification is based on the way the virus replicates and uses its genetic material within the host cell. The other options, such as capsids, host organisms, ability to cause disease, or mechanism of getting into host cells, do not provide a comprehensive classification scheme for all types of viruses.

According to the Baltimore System, the Major Groups of Viruses