To cells that are defective in primer removal, you add fluorescent ribonucleotides when the cells are undergoing DNA replication. In this case, you observe that one strand glows more than the other not only near the replication fork but also at intervals along its length. Which strand glows in this way and why?
A)The leading strand glows in this way because it is synthesized continuously.
B)The leading strand glows in this way because its RNA primers are widely spaced.
C)The lagging strand glows in this way because it is synthesized continuously.
D)The lagging strand glows in this way because its RNA primers are closely spaced.

Question

Quizplus · Accepted Answer

The lagging strand glows more than the leading strand because it is synthesized discontinuously in short fragments, with an RNA primer for each fragment. These RNA primers are closely spaced, resulting in multiple intervals of fluorescence along the length of the lagging strand.

To Cells That Are Defective in Primer Removal, You Add