The enzyme responsible for joining Okazaki fragments together during DNA replication is:
A)DNA polymerase.
B)helicase.
C)topoisomerase II.
D)DNA ligase.
E)DNA replicase.

Question

Quizplus · Accepted Answer

Okazaki fragments are short, discontinuous segments of nucleotides on the lagging strand of DNA replication. DNA polymerase elongates the leading strand continuously, but on the lagging strand, Okazaki fragments must be synthesized in the opposite direction of the replication fork. This leaves short gaps between the fragments that must be sealed. DNA ligase is the enzyme responsible for joining the Okazaki fragments together into a continuous strand on the lagging strand.

The Enzyme Responsible for Joining Okazaki Fragments Together During DNA