Imagine that a doctor is culturing cells from a malignant melanoma and from a normal skin sample. How would you expect these two cell populations to differ?
A)Malignant melanoma cells would have telomeres that do not shorten during successive rounds of replication.
B)Normal skin cells would have telomeres that do not shorten during successive rounds of replication.
C)Malignant melanoma cells would have inactive telomerases and so their telomeres would shorten during successive rounds of replication.
D)Normal skin cells would have active telomerases that constantly replenish and lengthen telomeres.
E)Malignant melanoma cells would have active telomerases that constantly replenish and lengthen telomeres.

Question

Quizplus · Accepted Answer

Malignant melanoma cells have high levels of telomerase activity, which enables them to constantly replenish and lengthen their telomeres, allowing for unlimited cell division and growth. Normal skin cells, on the other hand, have limited telomerase activity and undergo gradual telomere shortening with each round of replication, ultimately leading to cellular senescence or programmed cell death.

Imagine That a Doctor Is Culturing Cells from a Malignant