The microtubules that form the mitotic spindle extend out from the centrosome. Where would you expect to find the plus (fast assembling) end of a spindle microtubule?

Question

Quizplus · Accepted Answer

The plus end of the spindle microtubule would be located away from the centrosome, at the kinetochore. This is because the kinetochore on a chromosome is where the microtubules attach and exert force to move the chromosome during cell division. Therefore, the microtubules need to have their plus ends oriented towards the kinetochore.

The Microtubules That Form the Mitotic Spindle Extend Out from the Centrosome