The MOST likely reason(s) a metastatic tumor cell might lose its connection to the basal lamina would be:
A)a change in the composition of the basal lamina.
B)the loss of integrin proteins from the cell's surface.
C)a change in the type of integrin proteins present on the cell's surface.
D)the loss of integrin proteins from the cell's surface, or a change in the type of integrin proteins present on the cell's surface.

Question

Quizplus · Accepted Answer

The basal lamina acts as a barrier that prevents tumor cells from invading surrounding tissues. Integrin proteins on the surface of the tumor cell help attach the cell to the basal lamina. Loss of integrin proteins or changes in the type of integrin proteins present on the cell surface can weaken the attachment between the tumor cell and basal lamina, resulting in the loss of connection. Additionally, changes in the composition of the basal lamina can also contribute to the loss of connection. Therefore, the most likely reason for a metastatic tumor cell to lose its connection to the basal lamina would be the loss of integrin proteins from the cell's surface or a change in the type of integrin proteins present on the cell's surface.

The MOST Likely Reason(s) a Metastatic Tumor Cell Might Lose