People who opposed tobacco use in America from the days of Columbus until the middle of the 19^th century did so:

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Opposition to tobacco use in America from the days of Columbus until the mid-19th century was based on a variety of grounds, including social, moral, economic, and xenophobic reasons. Medical and scientific grounds for opposing tobacco use became more prominent later, particularly in the 20th century as scientific understanding of tobacco's health effects developed.

People Who Opposed Tobacco Use in America from the Days