The regioselectivity and stereospecificity in the hydroboration-oxidation of an alkene is best described as:

Question

Quizplus · Accepted Answer

In hydroboration-oxidation of an alkene, the boron adds to the less substituted carbon while the hydrogen adds to the more substituted carbon, resulting in anti-Markovnikov orientation. Since the hydroboration step involves syn-addition, the overall reaction results in syn-addition with anti-Markovnikov orientation. Therefore, the best choice is option C: Anti-Markovnikov orientation with syn-addition.

The Regioselectivity and Stereospecificity in the Hydroboration-Oxidation of an Alkene