The following structure is a proteasome inhibitor that may find application in treating cervical cancer (J. Med. Chem. $\textbf{ 2011 }$ , 449). The halides in this structure may be classified as ________ and ________.

Question

The following structure is a proteasome inhibitor that may find application in treating cervical cancer (J. Med. Chem. $\textbf{     2011    }$ , 449). The halides in this structure may be classified as ________ and ________.

Quizplus · Accepted Answer

The halides in the structure are located on vicinal carbon atoms (adjacent carbons in the carbon chain) and are also part of an aryl ring system. Therefore, the halides may be classified as both vicinal and aryl. Option A is incorrect because vinyl halides are attached to sp2 hybridized carbon atoms with a double bond to a neighboring carbon, while the halides in the structure are attached to sp3 hybridized carbon atoms. Option C is incorrect because there are no vinyl halides in the structure. Option D is incorrect because geminal halides are attached to the same carbon atom, and the halides in this structure are on adjacent carbon atoms.

The Following Structure Is a Proteasome Inhibitor That May Find 2011 \textbf{ 2011 } 2011

The Following Structure Is a Proteasome Inhibitor That May Find $\textbf{ 2011 }$