To initiate a signal transduction pathway,a signal binds to a receptor protein usually located in the

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Receptor proteins for signal transduction pathways are typically located on the plasma membrane of a cell. This allows them to interact with signaling molecules outside of the cell and initiate a response inside the cell. While there are some exceptions (such as intracellular receptors for steroid hormones), the majority of signal transduction pathways begin with membrane-bound receptors.

To Initiate a Signal Transduction Pathway,a Signal Binds to a Receptor