Can a patient with the following results be given a nephrotoxic medication: urine volume-720 mL/24 h,urine creatinine-100 mg/dL,and serum creatinine-2.5 mg/dL?
A) No, clearance is 20 mL/min
B) No, clearance is 40 mL/min
C) Yes, clearance is 80 mL/min
D) Yes, clearance is 120 mL/min

Question

Quizplus · Accepted Answer

The patient's creatinine clearance is calculated as:
Creatinine clearance = (urine creatinine x urine output)/serum creatinine
= (100 mg/dL x 720 mL/24 h)/2.5 mg/dL
= 28.8 mL/min
This value indicates that the patient has moderate renal impairment and is at risk for further kidney damage from nephrotoxic medications. Therefore, nephrotoxic medications should not be administered to this patient. The correct answer is therefore A - No, clearance is 20 mL/min.

Can a Patient with the Following Results Be Given a Nephrotoxic