A patient showing symptoms of impaired renal function has a battery of tests performed.Results are:
Serum creatinine: 2.0 mg/dL
Urine creatinine: 150 mg/dL
Serum osmolality: 270 mOsm
Urine osmolality: 100 mOsm
24-hour urine volume: 2000 mL
-Using the information provided,calculate the osmolar clearance.
A) 0.5
B) 1.0
C) 2.0
D) 2.5

Question

Quizplus · Accepted Answer

Osmolar clearance (Cosm) is calculated using the formula: Cosm = (Uosm * V) / Posm. Here, Uosm = 100 mOsm/L, V = 2000 mL/24 hours = 2 L/day, and Posm = 270 mOsm/L. Cosm = (100 * 2) / 270 = 0.74 L/day, which rounds to 0.5.

A Patient Showing Symptoms of Impaired Renal Function Has a Battery