The presence of increased renal tubular epithelial cell casts is most indicative of:

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Increased renal tubular epithelial cell casts are most indicative of acute tubular necrosis, which is characterized by damage to the renal tubules and subsequent shedding of damaged cells into the urine. Nephrotic syndrome is characterized by proteinuria, not cellular casts. Fanconi syndrome is a rare condition where there is dysfunction of the renal tubules leading to the loss of several substances such as glucose in the urine. Acute pyelonephritis is characterized by leukocyte casts, not renal tubular epithelial cell casts.

The Presence of Increased Renal Tubular Epithelial Cell Casts Is