Confirmation of maple syrup urine disease is made on the basis of:
A) Urine color
B) A positive 2,4-dinitrophenylhydrazine test
C) A positive ferric chloride test
D) MS/MS

Question

Quizplus · Accepted Answer

Confirmation of maple syrup urine disease usually involves measuring the levels of amino acids in the blood through tandem mass spectrometry (MS/MS) testing. This is because the disease is caused by a deficiency in certain enzymes involved in the breakdown of branched-chain amino acids, which can lead to an accumulation of these amino acids in the blood and urine. Urine color, 2,4-dinitrophenylhydrazine test, and ferric chloride test are not specific tests for maple syrup urine disease.

Confirmation of Maple Syrup Urine Disease Is Made on the Basis